These are letters and postcards on scientific and personal matters, with a long letter (1958) about Fermi's career from Adolfo Amidei to Emilio Segrè.

The Scientists Collection is comprised of individual letters and small groups of correspondence from American, British, French, and German scientists during the past three centuries. Although the content is highly varied, there is significant strength in astronomy, natural history, conchology, and geology. Among the scientists better represented in the collection are the astronomers William Radcliffe Birt, J.F.W. Herschel, and Franz Xaver von Zach; the conchologists A.D. Brown, Fred L. Button, Otto Mörch, Alfred Newton, Christian M. Poulsen, Temple Prime, Benjamin Lewis Vulliamy, and A. G. Wetherby; the physical scientists George Biddell Airy, Arnold Sommerfeld, Ferdinand R. Hassler, and Max Planck; the archaeologist Jean François Nadaillac; the philosopher William Whewell; and the naturalists Walter Henry Bates, Robert Chambers, Edme Dupuget, Robert Kaye Greville, Joseph Henry, John Stevens Henslow, John Lubbock, and Herbert Spencer.

A gifted mathematician, Polish-born Stanislaw Ulam made contributions to set theory, topology, mathematical logic, and number theory, but is most widely remembered for his work in fostering the technical development of thermonuclear weapons. He was associated with Los Alamos Scientific Laboratories for most of the years between 1943 and 1965, and thereafter with the University of Colorado. These papers include personal and professional correspondence, manuscripts of both published and unpublished works, and memorabilia.